Nutrioz for Healthcare Professionals

Clinical Reference Guide — Molecular Intraoral Delivery (MID)

Technology Overview

Nutrioz oral sprays use Molecular Intraoral Delivery (MID) — a precision nutrient delivery system that administers micronutrients via a 0.06ml ultra-fine mist directly onto the buccal and sublingual mucosa. Absorption occurs through the capillary-rich mucosal tissue directly into systemic circulation, bypassing the gastrointestinal tract entirely.

Absorption Data

• Vitamin D3: University of Sheffield research confirms oral spray D3 achieves comparable serum 25(OH)D levels to tablet supplementation, with the advantage of eliminating swallowing risk
• Vitamin B12: PubMed-published studies demonstrate sublingual/buccal B12 absorption of up to 90% bioavailability — comparable to intramuscular injection
• General MID advantage: Up to 9x higher bioavailability vs standard oral tablets for applicable nutrients

Patient Suitability Criteria

Nutrioz MID oral sprays are clinically appropriate for patients with:

• Dysphagia (neurogenic, structural, or iatrogenic)
• Post-bariatric surgery (Roux-en-Y, sleeve gastrectomy, gastric band)
• Inflammatory bowel disease (Crohn's disease, ulcerative colitis)
• Celiac disease with intestinal malabsorption
• Pernicious anemia (B12 malabsorption due to intrinsic factor deficiency)
• COPD with B12 deficiency risk
• Chemotherapy-induced nausea preventing oral tablet compliance
• Elderly patients with reduced gastric acid and intrinsic factor

Biber Protocol® Connection

Nutrioz is a mentee in the Biber Protocol® — a clinical framework establishing safe nutrient delivery standards for patients with swallowing difficulties. This provides a recognised clinical reference point for recommending Nutrioz products in dysphagia management.

Prescribing Considerations

• No known drug interactions specific to the delivery method
• Touch-free, sterile spray mechanism reduces infection risk in immunocompromised patients
• Zero fillers, allergens, or FODMAP sugars — suitable for patients with multiple sensitivities
• Manufactured in cGMP, FDA-registered, ISO-certified facilities

Clinical Supply & Formulary Enquiries

For clinical supply agreements, formulary inclusion enquiries, or patient sample requests, please contact our clinical partnerships team through the Nutrioz website.

Nutrioz products are food supplements, not medicines. They should not replace prescribed medications. Always use clinical judgement when recommending supplements to patients.